Basic Information
ID: ALA4182255
Type: ADME
Description: Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by substrate addition measured after 1 hr by TR-FRET assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Bromodomain-containing protein 2(ALA1293289)
Document: ALA4177706
Inhibition of recombinant human BRD2 bromodomain 1 (49 to 170 residues) using biotin labeled peptide substrate preincubated for 15 mins followed by substrate addition measured after 1 hr by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4182255
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.00 | 5.53 | 5.53 |
| 434.92 | 6.00 | 6.00 |
| 355.44 | 4.00 | 4.00 |
| 372.49 | 4.74 | 4.74 |
| 355.44 | 4.00 | 4.00 |
| 356.42 | 4.27 | 4.27 |
| 356.42 | 4.27 | 4.27 |
| 372.49 | 4.74 | 4.74 |