Basic Information
ID: ALA4182273
Type: Binding
Description: Inhibition of recombinant human PDE2A catalytic domain (580 to 919 residues) expressed in Escherichia coli BL21 (Codonplus) using [3H]cGMP as substrate after 15 mins by liquid scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4182273
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 301.69 | -1.33 | -1.33 |
| 277.37 | 2.30 | 2.30 |
| 285.69 | -0.30 | -0.30 |
| 303.68 | -0.35 | -0.35 |
| 269.24 | -1.00 | -1.00 |
| 285.69 | -0.30 | -0.30 |
| 393.81 | 1.88 | 1.88 |
| 411.80 | 2.01 | 2.01 |
| 403.80 | 1.42 | 1.42 |
| 301.69 | -1.33 | -1.33 |
| 331.72 | -1.97 | -1.97 |
| 418.82 | 1.75 | 1.75 |
| 483.93 | 4.10 | 4.10 |
| 428.25 | 2.53 | 2.53 |
| 428.25 | 2.53 | 2.53 |
| 472.70 | 2.64 | 2.64 |
| 428.25 | 2.53 | 2.53 |