Basic Information
ID: ALA4182832
Type: Binding
Description: Inhibition of MRP1 (unknown origin) expressed in BHK21 cells assessed as GSH efflux at 20 uM incubated for 3 hrs measured every 30 secs for 2 mins by GSH reductase enzyme based assay (Rvb = 100%)
Format: BAO_0000219
Organism: Homo sapiens
Target: Multidrug resistance-associated protein 1(ALA3004)
Document: ALA4177736
Inhibition of MRP1 (unknown origin) expressed in BHK21 cells assessed as GSH efflux at 20 uM incubated for 3 hrs measured every 30 secs for 2 mins by GSH reductase enzyme based assay (Rvb = 100%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4182832
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 445.57 | 4.01 | 4.01 |
| 482.63 | 5.35 | 5.35 |
| 450.63 | 5.07 | 5.07 |
| 436.60 | 4.68 | 4.68 |
| 535.49 | 5.45 | 5.45 |
| 436.60 | 4.68 | 4.68 |
| 502.62 | 4.40 | 4.40 |
| 450.63 | 5.07 | 5.07 |