Basic Information
ID: ALA4182835
Type: Binding
Description: Inhibition of P-gp (unknown origin) expressed in mouse NIH/3T3 cells assessed as reduction in rhodamine 123 efflux at 20 uM incubated for 30 mins by flow cytometric analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4177736
Inhibition of P-gp (unknown origin) expressed in mouse NIH/3T3 cells assessed as reduction in rhodamine 123 efflux at 20 uM incubated for 30 mins by flow cytometric analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4182835
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.62 | 4.99 | 4.99 |
| 495.63 | 5.16 | 5.16 |
| 445.57 | 4.01 | 4.01 |
| 482.63 | 5.35 | 5.35 |
| 501.59 | 4.59 | 4.59 |
| 495.63 | 5.16 | 5.16 |
| 482.63 | 5.35 | 5.35 |
| 448.61 | 4.82 | 4.82 |
| 501.59 | 4.59 | 4.59 |
| 448.61 | 4.82 | 4.82 |
| 450.63 | 5.07 | 5.07 |
| 535.49 | 5.45 | 5.45 |
| 491.04 | 5.34 | 5.34 |
| 501.59 | 4.59 | 4.59 |
| 436.60 | 4.68 | 4.68 |
| 501.59 | 4.59 | 4.59 |
| 445.57 | 4.01 | 4.01 |
| 502.62 | 4.40 | 4.40 |
| 491.04 | 5.34 | 5.34 |
| 535.49 | 5.45 | 5.45 |
| 436.60 | 4.68 | 4.68 |
| 502.62 | 4.40 | 4.40 |
| 470.62 | 4.99 | 4.99 |
| 450.63 | 5.07 | 5.07 |