Basic Information
ID: ALA4185127
Type: Binding
Description: Inhibition of SIRT1 (unknown origin) assessed as reduction in Fluor de Lys deacetylation at 10 to 20 uM incubated for 5 mins followed by substrate addition measured after 45 mins in presence of NAD/NADH by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 1(ALA4506)
Document: ALA4184125
Inhibition of SIRT1 (unknown origin) assessed as reduction in Fluor de Lys deacetylation at 10 to 20 uM incubated for 5 mins followed by substrate addition measured after 45 mins in presence of NAD/NADH by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4185127
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 228.25 | 2.97 | 2.97 |
| 122.13 | 0.18 | 0.18 |
| 785.03 | 2.15 | 2.15 |
| 767.01 | 2.95 | 2.95 |
| 785.02 | 2.15 | 2.15 |
| 620.87 | 4.10 | 4.10 |
| 638.88 | 3.30 | 3.30 |
| 785.03 | 2.15 | 2.15 |
| 622.88 | 4.32 | 4.32 |
| 622.88 | 4.32 | 4.32 |
| 785.03 | 2.15 | 2.15 |
| 492.74 | 4.44 | 4.44 |
| 638.88 | 3.30 | 3.30 |
| 638.88 | 3.30 | 3.30 |
| 638.88 | 3.30 | 3.30 |
| 767.01 | 2.95 | 2.95 |
| 494.76 | 4.67 | 4.67 |
| 476.74 | 5.47 | 5.47 |
| 504.80 | 6.52 | 6.52 |
| 494.76 | 4.67 | 4.67 |
| 620.87 | 4.10 | 4.10 |
| 476.74 | 5.47 | 5.47 |