Basic Information
ID: ALA4185178
Type: Functional
Description: Anti-inflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release pre-incubated for 5 mins before fMLP/CB stimulation using MeO-Suc-Ala-Ala-Pro-Val-pnitroanilide as substrate
Organism: Homo sapiens
Cell type: Neutrophil
Activity Charts
Bioactivity
Activity Types for Assay ALA4185178
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.09 | 7.09 |
| 464.83 | 5.55 | 5.55 |
| 358.39 | 2.69 | 2.69 |
| 358.39 | 3.19 | 3.19 |
| 358.39 | 3.19 | 3.19 |
| 498.75 | 7.80 | 7.80 |
| 624.59 | -1.02 | -1.02 |
| 318.46 | 4.78 | 4.78 |
| 372.42 | 3.49 | 3.49 |
| 334.46 | 4.66 | 4.66 |
| 334.46 | 4.66 | 4.66 |
| 486.78 | 8.10 | 8.10 |
| 320.47 | 4.57 | 4.57 |
| 264.28 | 1.56 | 1.56 |
| 320.47 | 4.57 | 4.57 |
| 458.68 | 6.70 | 6.70 |
| 474.73 | 7.14 | 7.14 |
| 472.71 | 6.06 | 6.06 |
| 516.81 | 7.73 | 7.73 |
| 444.74 | 7.53 | 7.53 |
| 318.41 | 4.05 | 4.05 |
| 508.52 | -0.28 | -0.28 |
| 334.46 | 3.89 | 3.89 |
| 348.48 | 4.75 | 4.75 |
| 486.78 | 7.59 | 7.59 |
| 168.15 | -0.44 | -0.44 |
| 336.47 | 3.54 | 3.54 |
| 320.47 | 4.57 | 4.57 |