Assay Report Card

Basic Information

ID: ALA4185351

Type: ADME

Description: Substrate activity at CYP3A5 in human liver microsomes assessed as enzyme-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation in presence of 3'-phosphoadenosine-5'-phosphosulfate by UFLC-DAD analysis

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
538.594.944.94