Assay Report Card

Basic Information

ID: ALA4185354

Type: ADME

Description: Substrate activity at CYP2A6 in human liver microsomes with NADPH-generating system assessed as CYP2A6-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 uM after 25 mins in presence of 8-methoxypsoralen

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
538.594.944.94