ID: ALA4185354
Type: ADME
Description: Substrate activity at CYP2A6 in human liver microsomes with NADPH-generating system assessed as CYP2A6-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 5 uM after 25 mins in presence of 8-methoxypsoralen
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Bioactivity
Activity Types for Assay ALA4185354
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
538.59 | 4.94 | 4.94 |