ID: ALA4185387
Type: ADME
Description: Substrate activity at full length CYP3A5 F210L mutant (unknown origin) expressed in s9 cells assessed as enzyme-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation after 60 mins in presence of NADPH by UFLC-DAD analysis relative to wild type CYP3A5
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4185387
FC
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
538.59 | 4.94 | 4.94 |