Assay Report Card

Basic Information

ID: ALA4185387

Type: ADME

Description: Substrate activity at full length CYP3A5 F210L mutant (unknown origin) expressed in s9 cells assessed as enzyme-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation after 60 mins in presence of NADPH by UFLC-DAD analysis relative to wild type CYP3A5

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
538.594.944.94