Basic Information
ID: ALA4185393
Type: ADME
Description: Substrate activity at CYP3A5 in human HepG2 cell s9 fractions assessed as enzyme-mediated benzoic acid (6R,7S)-2,6,10-trihydroxy-1,3,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-dibenzo[a,c]cycloocten-5-yl ester formation at 50 uM after 60 mins by LC-MS/MS analysis
Organism: Homo sapiens
Subcellular Fraction: S9 Fraction
Activity Charts
Bioactivity
Activity Types for Assay ALA4185393
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 538.59 | 4.94 | 4.94 |