Basic Information
ID: ALA4185405
Type: Binding
Description: Inhibition of FAM-labeled ZBA248 binding to recombinant human N-terminal His6-tagged BRD4 bromodomain 2 (333 to 460 residues) expressed in Rosetta2 DE3 cells after 30 mins by Flourescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4185405
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.90 | 3.66 | 3.66 |
| 457.00 | 5.53 | 5.53 |
| 415.45 | 4.16 | 4.16 |
| 437.50 | 6.16 | 6.16 |
| 435.49 | 5.92 | 5.92 |
| 435.49 | 5.92 | 5.92 |
| 449.51 | 6.22 | 6.22 |
| 402.46 | 4.41 | 4.41 |
| 361.36 | 4.05 | 4.05 |
| 435.49 | 5.92 | 5.92 |
| 503.48 | 6.93 | 6.93 |
| 424.46 | 6.11 | 6.11 |
| 359.39 | 4.39 | 4.39 |
| 423.48 | 5.85 | 5.85 |
| 435.49 | 5.92 | 5.92 |
| 409.45 | 5.54 | 5.54 |
| 328.76 | 4.04 | 4.04 |
| 435.49 | 5.92 | 5.92 |
| 424.46 | 5.24 | 5.24 |
| 435.49 | 5.92 | 5.92 |
| 435.49 | 5.92 | 5.92 |
| 388.43 | 4.40 | 4.40 |
| 427.44 | 5.68 | 5.68 |
| 410.44 | 4.71 | 4.71 |
| 360.38 | 3.78 | 3.78 |
| 410.44 | 4.73 | 4.73 |
| 360.38 | 3.58 | 3.58 |
| 449.51 | 6.22 | 6.22 |
| 441.47 | 5.99 | 5.99 |
| 414.47 | 4.97 | 4.97 |
| 411.43 | 4.13 | 4.13 |
| 389.42 | 4.66 | 4.66 |
| 414.47 | 4.96 | 4.96 |
| 424.46 | 4.95 | 4.95 |
| 360.37 | 4.65 | 4.65 |
| 465.51 | 5.92 | 5.92 |
| 410.44 | 4.93 | 4.93 |