Basic Information
ID: ALA4186353
Type: ADME
Description: Prodrug activation assessed as human PSA mediated 4-((S)-2-((S)-2-Amino-3-hydroxypropanamido)-4-methylpentanamido)benzyl(R)-1-(((2R,3R,11bS)-3-ethyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl)methyl)-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate formation at 200 uM after 6 hrs by HPLC-MS analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4186353
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1552.84 |