Assay Report Card

Basic Information

ID: ALA4186600

Type: Functional

Description: Antitussive activity in ammonia liquor-induced cough ICR mouse model assessed as reduction in cough frequency at 50 mg/kg, po treated with ammonia 1 hr before and 1 hr after test compound dosing measured for 3 mins relative to control

Organism: Mus musculus

Strain: ICR

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
256.262.702.70
338.404.474.47
270.283.003.00
822.942.252.25
322.364.384.38
418.400.170.17
368.394.094.09
525.603.403.40
422.485.305.30
550.51-1.26-1.26
550.51-1.36-1.36