Basic Information
ID: ALA4186807
Type: ADME
Description: Inhibition of cynomolgus monkey adrenal mitochondrial CYP11B1 using 11-deoxycortisol as substrate after 90 mins in presence of NADPH by mass spectrometric analysis
Organism: Macaca fascicularis
Activity Charts
Bioactivity
Activity Types for Assay ALA4186807
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.28 | 2.68 | 2.68 |
| 238.29 | 2.66 | 2.66 |
| 241.29 | 3.50 | 3.50 |
| 227.24 | 2.43 | 2.43 |
| 292.34 | 3.29 | 3.29 |
| 368.43 | 2.63 | 2.63 |
| 280.33 | 3.29 | 3.29 |
| 255.32 | 3.42 | 3.42 |
| 273.31 | 3.56 | 3.56 |
| 333.41 | 2.82 | 2.82 |
| 298.34 | 2.52 | 2.52 |
| 266.34 | 3.65 | 3.65 |
| 285.34 | 3.43 | 3.43 |
| 266.30 | 2.90 | 2.90 |
| 395.46 | 2.33 | 2.33 |
| 356.42 | 2.48 | 2.48 |
| 241.29 | 3.03 | 3.03 |
| 227.26 | 2.78 | 2.78 |