Basic Information
ID: ALA4186870
Type: Binding
Description: Inverse agonist activity at RORgammat in human Jurkat cells assessed as inhibition of transcriptional activity after overnight incubation by human IL-17 ROR response element driven-bright-glo luciferase reporter gene assay
Organism: Homo sapiens
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA4186870
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.51 | 4.37 | 4.37 |
| 447.54 | 4.13 | 4.13 |
| 436.58 | ||
| 437.57 | ||
| 437.50 | 4.14 | 4.14 |
| 463.61 | ||
| 459.55 | 4.06 | 4.06 |
| 461.56 | 4.52 | 4.52 |
| 420.51 | 5.04 | 5.04 |
| 421.50 | 4.43 | 4.43 |
| 461.56 | 4.18 | 4.18 |
| 461.56 | 4.00 | 4.00 |
| 433.51 | 3.79 | 3.79 |
| 461.56 | 4.44 | 4.44 |
| 405.45 | 3.14 | 3.14 |
| 489.55 | ||
| 489.55 | ||
| 453.57 | ||
| 475.59 | 4.91 | 4.91 |
| 461.56 | 4.16 | 4.16 |
| 481.98 | 4.79 | 4.79 |
| 489.55 |