Basic Information
ID: ALA4186871
Type: Functional
Description: In vivo inverse agonist activity at RORgammat in Balb/c mouse assessed as inhibition of IL-23-induced IL-17a gene expression at 100 mg/kg, po administered 30 mins before and 8 hrs after IL-23 injection in ears intradermally measured after 24 hrs by qRT-PCR analysis relative to control
Organism: Mus musculus
Strain: Balb/c
Activity Charts
Bioactivity
Activity Types for Assay ALA4186871
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.55 |