Assay Report Card

Basic Information

ID: ALA4187195

Type: Binding

Description: Inhibition of recombinant human full length N-terminal GST-tagged CK1epsilon expressed in baculovirus in Sf9 insect cells using ULight-Topo-IIa(Thr1342) peptide as substrate after 10 mins by TR-FRET assay

Organism: Homo sapiens

Cell type: Sf9

Activity Charts

Bioactivity

Activity Types for Assay ALA4187195

IC50

Total(66)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
510.94	3.38	3.38
463.45	2.81	2.81
400.39	1.97	1.97
481.54	3.40	3.40
474.96	3.10	3.10
498.44	3.70	3.70
502.60	3.16	3.16
496.52	4.27	4.27
508.51	4.34	4.34
463.45	2.81	2.81
461.92	3.19	3.19
460.93	2.76	2.76
507.52	4.23	4.23
419.46	3.11	3.11
471.50	4.06	4.06
468.49	3.48	3.48
487.56	4.53	4.53
463.45	2.81	2.81
530.46	4.44	4.44
498.44	3.70	3.70
414.42	2.45	2.45
521.55	4.25	4.25
422.44	3.54	3.54
498.44	3.70	3.70
427.47	2.54	2.54
495.38	3.42	3.42
463.45	2.81	2.81
476.50	2.73	2.73
508.51	3.93	3.93
507.52	3.91	3.91
470.51	3.79	3.79
477.48	3.12	3.12
537.55	3.86	3.86
490.52	3.04	3.04
503.59	2.55	2.55
461.53	4.01	4.01
480.45	3.56	3.56
509.41	3.76	3.76
410.36	3.30	3.30
405.44	2.80	2.80
523.52	3.47	3.47
419.46	3.11	3.11
528.52	2.96	2.96
480.45	3.56	3.56
508.51	4.56	4.56
457.50	2.54	2.54
456.51	2.12	2.12
476.50	2.73	2.73
498.44	3.70	3.70
454.42	3.13	3.13
497.90	3.47	3.47
494.49	2.87	2.87
445.46	3.54	3.54
394.41	2.13	2.13
476.50	2.73	2.73
426.49	2.11	2.11
470.54	2.46	2.46
498.44	3.70	3.70
476.49	3.73	3.73
405.44	2.80	2.80
492.47	3.89	3.89
440.52	2.45	2.45
476.50	2.73	2.73
481.44	2.95	2.95
496.36	3.84	3.84
466.47	4.93	4.93