Basic Information
ID: ALA4187202
Type: ADME
Description: Inhibition of CYP2C9 in human liver microsomes using tolbutamide as substrate at 10 uM after 10 mins in presence of NADPH relative to control
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4187202
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.54 | 3.40 | 3.40 |
| 498.44 | 3.70 | 3.70 |
| 463.45 | 2.81 | 2.81 |
| 461.92 | 3.19 | 3.19 |
| 419.46 | 3.11 | 3.11 |
| 468.49 | 3.48 | 3.48 |
| 463.45 | 2.81 | 2.81 |
| 498.44 | 3.70 | 3.70 |
| 414.42 | 2.45 | 2.45 |
| 422.44 | 3.54 | 3.54 |
| 495.38 | 3.42 | 3.42 |
| 463.45 | 2.81 | 2.81 |
| 461.53 | 4.01 | 4.01 |
| 480.45 | 3.56 | 3.56 |
| 509.41 | 3.76 | 3.76 |
| 405.44 | 2.80 | 2.80 |
| 498.44 | 3.70 | 3.70 |
| 445.46 | 3.54 | 3.54 |
| 405.44 | 2.80 | 2.80 |
| 476.50 | 2.73 | 2.73 |
| 481.44 | 2.95 | 2.95 |
| 496.36 | 3.84 | 3.84 |