Assay Report Card

Basic Information

ID: ALA4187203

Type: ADME

Description: Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate at 10 uM after 10 mins in presence of NADPH relative to control

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
481.543.403.40
498.443.703.70
463.452.812.81
461.923.193.19
419.463.113.11
468.493.483.48
463.452.812.81
498.443.703.70
414.422.452.45
422.443.543.54
495.383.423.42
463.452.812.81
461.534.014.01
480.453.563.56
509.413.763.76
405.442.802.80
498.443.703.70
445.463.543.54
405.442.802.80
476.502.732.73
481.442.952.95
496.363.843.84