Assay Report Card

Basic Information

ID: ALA4187204

Type: ADME

Description: Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate at 10 uM after 10 mins in presence of NADPH relative to control

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: microsomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
481.543.403.40
498.443.703.70
463.452.812.81
461.923.193.19
419.463.113.11
468.493.483.48
463.452.812.81
498.443.703.70
414.422.452.45
422.443.543.54
495.383.423.42
463.452.812.81
461.534.014.01
480.453.563.56
509.413.763.76
405.442.802.80
498.443.703.70
445.463.543.54
405.442.802.80
476.502.732.73
481.442.952.95
496.363.843.84