Basic Information
ID: ALA4187421
Type: Binding
Description: Inhibition of N-terminal GST-HIS6 fusion protein tagged human full length CDK9 (M1 to F372 residues)/N-terminal GST-HIS6 fusion protein tagged human Cyclin-T1 (M1 to K726 residues) expressed in Sf9 cells at 10 uM using TAMRA-Rbtide substrate and ATP incubated for 1 hr by fluorescent polarization assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4187421
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.50 | 2.28 | 2.28 |
| 454.54 | 3.86 | 3.86 |
| 469.50 | 4.44 | 4.44 |
| 481.53 | 4.31 | 4.31 |
| 339.33 | 3.73 | 3.73 |
| 487.49 | 4.58 | 4.58 |
| 490.37 | 5.60 | 5.60 |
| 439.52 | 4.15 | 4.15 |
| 483.53 | 4.83 | 4.83 |
| 499.98 | 5.34 | 5.34 |
| 491.50 | 4.98 | 4.98 |
| 487.49 | 4.58 | 4.58 |
| 407.48 | 5.29 | 5.29 |
| 485.95 | 4.95 | 4.95 |
| 433.44 | 4.89 | 4.89 |
| 425.47 | 5.43 | 5.43 |
| 486.55 | 4.39 | 4.39 |
| 368.37 | 3.14 | 3.14 |
| 404.35 | 3.42 | 3.42 |
| 386.36 | 3.28 | 3.28 |
| 469.50 | 4.44 | 4.44 |
| 497.55 | 5.22 | 5.22 |
| 390.42 | 5.31 | 5.31 |
| 457.51 | 4.29 | 4.29 |
| 469.50 | 4.44 | 4.44 |
| 472.53 | 4.00 | 4.00 |
| 469.50 | 4.44 | 4.44 |
| 503.01 | 4.90 | 4.90 |
| 490.52 | 4.13 | 4.13 |
| 469.50 | 4.44 | 4.44 |
| 484.56 | 3.87 | 3.87 |
| 497.55 | 5.22 | 5.22 |
| 414.41 | 4.06 | 4.06 |
| 425.47 | 5.43 | 5.43 |
| 386.36 | 3.28 | 3.28 |
| 453.50 | 4.74 | 4.74 |
| 400.39 | 3.67 | 3.67 |
| 374.32 | 3.41 | 3.41 |
| 457.51 | 4.29 | 4.29 |
| 451.51 | 4.30 | 4.30 |
| 485.57 | 5.15 | 5.15 |
| 487.99 | 5.20 | 5.20 |
| 471.54 | 4.68 | 4.68 |
| 483.53 | 4.83 | 4.83 |
| 451.51 | 4.30 | 4.30 |
| 457.46 | 4.57 | 4.57 |
| 485.95 | 4.95 | 4.95 |
| 487.49 | 4.58 | 4.58 |
| 490.52 | 4.13 | 4.13 |
| 472.53 | 4.00 | 4.00 |
| 416.84 | 4.19 | 4.19 |
| 472.53 | 4.00 | 4.00 |
| 473.92 | 5.09 | 5.09 |