Basic Information
ID: ALA4187427
Type: Binding
Description: Inhibition of C-terminal 6-His tagged recombinant Clostridium difficile toxin B catalytic fragment (Met1 to Leu543 residues) assessed as reduction in glucosyltransferase domain UDP-glucose hydrolysis activity using UDP-glucose and ADP Alexa633 tracer incubated fore 3 hrs by fluorescence polarization assay
Organism: Clostridioides difficile
Activity Charts
Bioactivity
Activity Types for Assay ALA4187427
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.91 | 4.63 | 4.63 |
| 511.97 | 4.59 | 4.59 |
| 511.97 | 4.59 | 4.59 |
| 511.97 | 4.59 | 4.59 |
| 420.85 | 4.37 | 4.37 |
| 419.41 | 3.12 | 3.12 |
| 448.91 | 4.55 | 4.55 |
| 503.77 | 5.55 | 5.55 |
| 400.86 | 4.05 | 4.05 |
| 459.89 | 4.12 | 4.12 |
| 435.87 | 3.64 | 3.64 |
| 502.79 | 4.95 | 4.95 |
| 435.87 | 3.64 | 3.64 |
| 449.89 | 3.66 | 3.66 |
| 483.35 | 5.21 | 5.21 |
| 515.96 | 4.49 | 4.49 |
| 448.91 | 4.55 | 4.55 |
| 358.78 | 3.02 | 3.02 |
| 401.42 | 2.99 | 2.99 |
| 450.88 | 3.95 | 3.95 |
| 512.96 | 3.98 | 3.98 |
| 469.32 | 4.90 | 4.90 |
| 448.91 | 4.55 | 4.55 |
| 469.32 | 4.90 | 4.90 |
| 450.88 | 3.95 | 3.95 |
| 435.87 | 3.64 | 3.64 |
| 435.87 | 3.64 | 3.64 |
| 518.00 | 4.65 | 4.65 |
| 511.97 | 4.59 | 4.59 |
| 435.87 | 3.64 | 3.64 |
| 469.32 | 4.90 | 4.90 |
| 469.32 | 4.90 | 4.90 |
| 440.93 | 4.97 | 4.97 |
| 542.98 | 3.99 | 3.99 |
| 436.86 | 3.03 | 3.03 |
| 512.96 | 3.98 | 3.98 |
| 526.00 | 4.90 | 4.90 |
| 435.87 | 3.64 | 3.64 |
| 542.00 | 4.60 | 4.60 |
| 441.90 | 3.70 | 3.70 |
| 510.98 | 5.19 | 5.19 |
| 431.45 | 2.99 | 2.99 |
| 434.88 | 4.24 | 4.24 |
| 449.89 | 3.73 | 3.73 |
| 452.87 | 4.38 | 4.38 |