Basic Information
ID: ALA4189064
Type: Binding
Description: Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS at 10 uM using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addition measured after 60 mins by MALDI-TOF MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4189064
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 77.15 | -0.13 | -0.13 |
| 116.08 | -0.40 | -0.40 |
| 189.07 | ||
| 274.18 | ||
| 208.22 | 2.46 | 2.46 |
| 158.16 | 1.62 | 1.62 |
| 296.55 | 3.62 | 3.62 |
| 171.27 | 1.54 | 1.54 |
| 188.94 | ||
| 240.44 | 2.06 | 2.06 |
| 220.32 | 3.28 | 3.28 |
| 612.64 | -3.88 | -3.88 |
| 307.33 | -2.21 | -2.21 |
| 178.14 | -0.25 | -0.25 |
| 225.21 | 0.29 | 0.29 |
| 312.13 | ||
| 191.52 | ||
| 235.97 | ||
| 302.19 |