Basic Information
ID: ALA4189067
Type: Binding
Description: Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addition measured after 60 mins by MALDI-TOF MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4189067
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 77.15 | -0.13 | -0.13 |
| 116.08 | -0.40 | -0.40 |
| 189.07 | ||
| 274.18 | ||
| 208.22 | 2.46 | 2.46 |
| 158.16 | 1.62 | 1.62 |
| 296.55 | 3.62 | 3.62 |
| 171.27 | 1.54 | 1.54 |
| 188.94 | ||
| 240.44 | 2.06 | 2.06 |
| 220.32 | 3.28 | 3.28 |
| 612.64 | -3.88 | -3.88 |
| 307.33 | -2.21 | -2.21 |
| 178.14 | -0.25 | -0.25 |
| 225.21 | 0.29 | 0.29 |
| 312.13 | ||
| 191.52 | ||
| 235.97 | ||
| 302.19 |