Basic Information
ID: ALA4189284
Type: Binding
Description: Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4189284
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 189.26 | 2.37 | 2.37 |
| 457.00 | 5.53 | 5.53 |
| 434.92 | 6.00 | 6.00 |
| 370.41 | 2.60 | 2.60 |
| 306.41 | 3.84 | 3.84 |
| 336.44 | 3.33 | 3.33 |
| 294.40 | 3.76 | 3.76 |
| 335.45 | 3.30 | 3.30 |
| 372.47 | 4.30 | 4.30 |
| 336.44 | 3.85 | 3.85 |
| 336.44 | 3.33 | 3.33 |
| 414.51 | 4.00 | 4.00 |
| 413.52 | 4.60 | 4.60 |
| 322.41 | 3.54 | 3.54 |
| 338.41 | 3.54 | 3.54 |
| 375.52 | 4.22 | 4.22 |
| 384.86 | 4.19 | 4.19 |
| 349.43 | 2.94 | 2.94 |
| 324.38 | 3.15 | 3.15 |
| 413.52 | 4.60 | 4.60 |
| 415.50 | 3.39 | 3.39 |
| 349.48 | 3.90 | 3.90 |
| 370.50 | 5.51 | 5.51 |
| 386.50 | 4.60 | 4.60 |
| 364.45 | 3.84 | 3.84 |
| 310.35 | 2.76 | 2.76 |
| 331.42 | 3.71 | 3.71 |
| 350.42 | 3.54 | 3.54 |
| 366.46 | 3.21 | 3.21 |
| 360.46 | 4.23 | 4.23 |
| 364.45 | 3.47 | 3.47 |
| 387.48 | 4.19 | 4.19 |
| 294.40 | 3.84 | 3.84 |
| 397.48 | 4.17 | 4.17 |
| 378.47 | 4.02 | 4.02 |
| 373.29 | 4.60 | 4.60 |
| 457.53 | 2.89 | 2.89 |
| 280.37 | 3.45 | 3.45 |
| 280.37 | 3.37 | 3.37 |
| 280.37 | 3.45 | 3.45 |
| 320.44 | 4.15 | 4.15 |
| 322.41 | 3.54 | 3.54 |
| 308.43 | 4.15 | 4.15 |
| 361.45 | 4.49 | 4.49 |
| 401.51 | 4.91 | 4.91 |
| 371.48 | 4.90 | 4.90 |
| 266.34 | 3.06 | 3.06 |
| 376.50 | 4.64 | 4.64 |
| 417.55 | 3.71 | 3.71 |