Basic Information
ID: ALA4189498
Type: Binding
Description: Inhibition of MNK1/2 in human HeLa cells assessed as decrease in eIF4E phosphorylation at Ser209 after 2 hrs by AlphaScreen assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4189498
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.49 | 4.39 | 4.39 |
| 409.45 | 3.41 | 3.41 |
| 421.50 | 3.93 | 3.93 |
| 440.51 | 2.55 | 2.55 |
| 397.48 | 3.45 | 3.45 |
| 450.55 | 4.10 | 4.10 |
| 268.28 | 2.06 | 2.06 |
| 408.47 | 2.98 | 2.98 |
| 441.49 | 3.07 | 3.07 |
| 413.48 | 3.16 | 3.16 |
| 400.44 | 3.24 | 3.24 |
| 408.46 | 4.01 | 4.01 |
| 431.93 | 4.10 | 4.10 |
| 465.48 | 4.47 | 4.47 |
| 411.51 | 3.76 | 3.76 |
| 330.35 | 2.87 | 2.87 |
| 287.32 | 3.77 | 3.77 |
| 422.49 | 3.32 | 3.32 |
| 409.45 | 3.41 | 3.41 |
| 456.51 | 2.57 | 2.57 |
| 413.48 | 3.16 | 3.16 |
| 450.55 | 4.10 | 4.10 |
| 422.49 | 3.32 | 3.32 |
| 441.49 | 3.15 | 3.15 |