Basic Information
ID: ALA4189504
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 5 mins followed by NADPH addition by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4189504
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.45 | 3.41 | 3.41 |
| 421.50 | 3.93 | 3.93 |
| 450.55 | 4.10 | 4.10 |
| 408.46 | 4.01 | 4.01 |
| 330.35 | 2.87 | 2.87 |
| 422.49 | 3.32 | 3.32 |
| 409.45 | 3.41 | 3.41 |
| 422.49 | 3.32 | 3.32 |