ID: ALA4189661
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as (S)-N-(4-amino-5-(4-(4-hydroxyphenoxy)phenyl)-6-methylene-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)acrylamide formation after 3 hrs
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsome
Target: ADMET(ALA612558)
Document: ALA4184325
Drug metabolism in human liver microsomes assessed as (S)-N-(4-amino-5-(4-(4-hydroxyphenoxy)phenyl)-6-methylene-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)acrylamide formation after 3 hrs: 1
Bioactivity
Activity Types for Assay ALA4189661
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
423.48 | 4.17 | 4.17 |