Drug metabolism in human liver microsomes assessed as (S,E)-N-(4-amino-6-methylene-5-(4-phenoxyphenyl)-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)-...

Basic Information

ID: ALA4189664

Type: ADME

Description: Drug metabolism in human liver microsomes assessed as (S,E)-N-(4-amino-6-methylene-5-(4-phenoxyphenyl)-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)-3-hydroxyacrylamide formation after 3 hrs

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: microsome

Target: ADMET(ALA612558)

Document: ALA4184325

Drug metabolism in human liver microsomes assessed as (S,E)-N-(4-amino-6-methylene-5-(4-phenoxyphenyl)-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)-3-hydroxyacrylamide formation after 3 hrs: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4189664

Drug metabolism

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
423.48	4.17	4.17

Parent Molecular Weight

ALogP

Polar Surface Area

423.48

4.17

Drug metabolism in human liver microsomes assessed as (S,E)-N-(4-amino-6-methylene-5-(4-phenoxyphenyl)-7,8-dihydro-6H-pyrimido[5,4-b]pyrrolizin-7-yl)-...

Basic Information

Activity Charts

Compound Summary