Assay Report Card

Basic Information

ID: ALA4189732

Type: Functional

Description: Antiproliferative activity against human TMD8 cells xenografted in CB17 SCID nude mouse assessed as decrease in Ki-67 expression at 15 mg/kg, po qd administered for 13 consecutive days measured on day 17 by hematoxylin and eosin staining-based immunohistochemical analysis

Organism: Homo sapiens

Cell type: TMD8

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
423.484.174.17