Basic Information
ID: ALA4189778
Type: Binding
Description: Binding affinity to menin in mouse bone marrow cells harboring MLL-AF9 fusion protein assessed as inhibition of protein interaction with MLL by measuring cell growth inhibition after 7 days by MTT assay
Format: BAO_0000219
Organism: Mus musculus
Target: Menin(ALA3124739)
Document: ALA4184328
Binding affinity to menin in mouse bone marrow cells harboring MLL-AF9 fusion protein assessed as inhibition of protein interaction with MLL by measuring cell growth inhibition after 7 days by MTT assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4189778
GI50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 484.55 | 5.53 | 5.53 |
| 638.76 | 5.17 | 5.17 |
| 596.73 | 4.91 | 4.91 |
| 667.81 | 4.50 | 4.50 |
| 624.74 | 4.78 | 4.78 |
| 674.82 | 5.31 | 5.31 |
| 638.81 | 6.04 | 6.04 |
| 637.78 | 6.66 | 6.66 |
| 675.81 | 3.83 | 3.83 |
| 706.88 | 6.73 | 6.73 |
| 610.75 | 5.25 | 5.25 |
| 674.82 | 4.58 | 4.58 |
| 611.69 | 4.91 | 4.91 |
| 595.74 | 6.40 | 6.40 |
| 689.83 | 4.09 | 4.09 |
| 652.79 | 5.56 | 5.56 |
| 623.75 | 6.27 | 6.27 |
| 673.83 | 6.07 | 6.07 |
| 597.67 | 4.52 | 4.52 |
| 674.74 | 5.42 | 5.42 |
| 656.75 | 5.12 | 5.12 |
| 728.79 | 5.47 | 5.47 |
| 720.91 | 7.12 | 7.12 |
| 597.67 | 4.52 | 4.52 |
| 564.64 | 5.78 | 5.78 |
| 688.85 | 4.97 | 4.97 |
| 597.67 | 4.52 | 4.52 |
| 597.71 | 5.34 | 5.34 |
| 692.73 | 5.71 | 5.71 |