Selectivity index, ratio of GI50 for mouse bone marrow cells transformed with control oncogenes Hoxa9/Meis1 to GI50 for binding affinity to menin in m...

Basic Information

ID: ALA4189780

Type: Unassigned

Description: Selectivity index, ratio of GI50 for mouse bone marrow cells transformed with control oncogenes Hoxa9/Meis1 to GI50 for binding affinity to menin in mouse bone marrow cells harboring MLL-AF9 fusion protein assessed as inhibition of protein interaction with MLL by measuring cell growth inhibition

Format: BAO_0000219

Organism: Mus musculus

Target:  Unchecked(ALA612545)

Document:  ALA4184328

Selectivity index, ratio of GI50 for mouse bone marrow cells transformed with control oncogenes Hoxa9/Meis1 to GI50 for binding affinity to menin in mouse bone marrow cells harboring MLL-AF9 fusion protein assessed as inhibition of protein interaction with MLL by measuring cell growth inhibition: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
597.674.524.52
597.674.524.52
597.674.524.52