Basic Information
ID: ALA4189797
Type: Functional
Description: In vivo inhibition of menin interaction with MLL in luciferase expressing human MV411 cells xenografted in NSG mouse assessed as decrease in HOXA9 gene expression in bone marrow at 80 mg/kg, ip administered for 6 consecutive days by qRT-PCR method relative to vehicle-treated control
Format: BAO_0000218
Organism: Mus musculus
Target: Mus musculus(ALA375)
Document: ALA4184328
In vivo inhibition of menin interaction with MLL in luciferase expressing human MV411 cells xenografted in NSG mouse assessed as decrease in HOXA9 gene expression in bone marrow at 80 mg/kg, ip administered for 6 consecutive days by qRT-PCR method relative to vehicle-treated control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4189797
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 597.67 | 4.52 | 4.52 |