Basic Information
ID: ALA4189927
Type: ADME
Description: Ratio of drug level in Wistar rat brain to plasma at 10 mg/kg, po measured at 1 hr by LC-MS/MS method
Organism: Rattus norvegicus
Strain: Wistar
Tissue: Brain/Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4189927
BPR
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 367.88 | 2.09 | 2.09 |
| 432.52 | 2.63 | 2.63 |
| 377.51 | 2.96 | 2.96 |
| 372.51 | 2.94 | 2.94 |
| 373.50 | 2.33 | 2.33 |
| 370.50 | 2.40 | 2.40 |
| 455.60 | 3.38 | 3.38 |
| 353.47 | 4.10 | 4.10 |
| 398.55 | 3.33 | 3.33 |
| 340.47 | 2.77 | 2.77 |
| 453.59 | 2.84 | 2.84 |
| 372.51 | 2.94 | 2.94 |
| 409.53 | 4.11 | 4.11 |
| 373.50 | 2.33 | 2.33 |
| 383.50 | 3.72 | 3.72 |
| 372.51 | 2.94 | 2.94 |
| 409.53 | 4.11 | 4.11 |
| 353.47 | 4.10 | 4.10 |
| 342.49 | 3.31 | 3.31 |
| 396.54 | 2.79 | 2.79 |
| 398.55 | 3.33 | 3.33 |
| 406.96 | 3.59 | 3.59 |
| 399.54 | 2.72 | 2.72 |
| 404.94 | 3.06 | 3.06 |
| 441.58 | 3.13 | 3.13 |
| 370.50 | 2.40 | 2.40 |
| 399.54 | 2.72 | 2.72 |
| 384.52 | 3.08 | 3.08 |
| 382.51 | 2.54 | 2.54 |
| 414.55 | 2.44 | 2.44 |
| 396.54 | 2.79 | 2.79 |
| 406.96 | 3.59 | 3.59 |
| 409.53 | 4.11 | 4.11 |
| 455.60 | 3.38 | 3.38 |
| 370.50 | 2.14 | 2.14 |
| 404.94 | 3.06 | 3.06 |
| 398.55 | 3.33 | 3.33 |
| 342.49 | 3.31 | 3.31 |
| 382.51 | 2.54 | 2.54 |
| 343.48 | 2.70 | 2.70 |
| 383.50 | 3.72 | 3.72 |
| 370.50 | 2.40 | 2.40 |
| 372.51 | 2.67 | 2.67 |
| 412.58 | 3.59 | 3.59 |
| 416.95 | 3.20 | 3.20 |
| 383.50 | 3.72 | 3.72 |
| 342.49 | 3.31 | 3.31 |