Basic Information
ID: ALA4189991
Type: Binding
Description: Inhibition of human ALDH1A1 using NAD+/propionaldehyde as substrate/cofactor preincubated for 15 mins followed by substrate/cofactor addition measured for 30 mins by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Aldehyde dehydrogenase 1A1(ALA3577)
Document: ALA4184337
Inhibition of human ALDH1A1 using NAD+/propionaldehyde as substrate/cofactor preincubated for 15 mins followed by substrate/cofactor addition measured for 30 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4189991
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 237.26 | 2.42 | 2.42 |
| 470.55 | 3.43 | 3.43 |
| 431.58 | 3.75 | 3.75 |
| 423.49 | 2.81 | 2.81 |
| 435.54 | 4.66 | 4.66 |
| 445.56 | 3.68 | 3.68 |
| 539.61 | 3.29 | 3.29 |
| 528.06 | 4.64 | 4.64 |
| 485.59 | 2.75 | 2.75 |
| 450.56 | 3.84 | 3.84 |
| 436.51 | 2.11 | 2.11 |
| 484.99 | 4.80 | 4.80 |
| 489.60 | 3.98 | 3.98 |
| 451.55 | 3.44 | 3.44 |
| 456.57 | 4.21 | 4.21 |
| 539.61 | 3.29 | 3.29 |
| 447.59 | 2.14 | 2.14 |
| 539.61 | 3.29 | 3.29 |
| 487.60 | 3.00 | 3.00 |
| 453.52 | 1.74 | 1.74 |
| 538.65 | 3.22 | 3.22 |
| 478.55 | 3.31 | 3.31 |
| 512.61 | 2.58 | 2.58 |
| 466.56 | 3.22 | 3.22 |
| 492.58 | 3.70 | 3.70 |
| 521.62 | 3.15 | 3.15 |
| 424.52 | 3.45 | 3.45 |
| 490.59 | 3.18 | 3.18 |
| 469.58 | 4.06 | 4.06 |
| 514.61 | 3.88 | 3.88 |
| 495.00 | 3.83 | 3.83 |
| 509.66 | 3.08 | 3.08 |
| 506.60 | 4.09 | 4.09 |
| 435.50 | 2.81 | 2.81 |
| 450.54 | 2.27 | 2.27 |
| 446.47 | 3.30 | 3.30 |
| 536.63 | 2.75 | 2.75 |
| 463.56 | 3.59 | 3.59 |
| 447.59 | 2.14 | 2.14 |
| 496.54 | 3.45 | 3.45 |
| 490.59 | 3.18 | 3.18 |
| 428.48 | 3.01 | 3.01 |
| 437.57 | 3.12 | 3.12 |
| 466.59 | 3.24 | 3.24 |
| 450.56 | 3.69 | 3.69 |
| 524.62 | 2.83 | 2.83 |
| 499.64 | 4.05 | 4.05 |
| 478.61 | 4.62 | 4.62 |
| 445.52 | 1.83 | 1.83 |
| 486.52 | 2.55 | 2.55 |
| 458.56 | 3.15 | 3.15 |
| 489.57 | 1.15 | 1.15 |
| 468.53 | 4.29 | 4.29 |
| 431.52 | 0.81 | 0.81 |
| 448.59 | 5.15 | 5.15 |
| 507.59 | 3.16 | 3.16 |
| 473.57 | 2.61 | 2.61 |
| 496.54 | 3.45 | 3.45 |
| 448.54 | 4.34 | 4.34 |
| 550.66 | 3.00 | 3.00 |
| 466.58 | 2.64 | 2.64 |
| 486.59 | 4.45 | 4.45 |
| 533.65 | 3.02 | 3.02 |
| 526.63 | 2.62 | 2.62 |
| 438.55 | 3.69 | 3.69 |
| 488.59 | 2.07 | 2.07 |
| 449.53 | 3.20 | 3.20 |
| 496.54 | 3.45 | 3.45 |
| 511.60 | 0.69 | 0.69 |
| 473.57 | 2.61 | 2.61 |
| 500.62 | 4.53 | 4.53 |
| 511.60 | 4.13 | 4.13 |
| 536.63 | 3.12 | 3.12 |
| 437.52 | 3.20 | 3.20 |
| 459.57 | 5.03 | 5.03 |
| 437.57 | 3.12 | 3.12 |
| 538.07 | 3.67 | 3.67 |
| 480.57 | 3.56 | 3.56 |
| 416.53 | 0.53 | 0.53 |
| 464.59 | 4.23 | 4.23 |
| 470.55 | 4.54 | 4.54 |
| 464.59 | 4.23 | 4.23 |
| 535.65 | 3.44 | 3.44 |
| 539.61 | 3.29 | 3.29 |
| 473.57 | 2.61 | 2.61 |
| 459.55 | 2.22 | 2.22 |
| 480.57 | 2.28 | 2.28 |
| 533.65 | 3.02 | 3.02 |
| 525.63 | 4.42 | 4.42 |
| 436.53 | 3.30 | 3.30 |
| 445.55 | 0.82 | 0.82 |
| 556.06 | 3.81 | 3.81 |
| 498.56 | 3.70 | 3.70 |
| 473.57 | 2.61 | 2.61 |
| 452.53 | 2.94 | 2.94 |
| 466.60 | 4.47 | 4.47 |
| 430.53 | 1.41 | 1.41 |
| 436.53 | 3.45 | 3.45 |
| 536.63 | 3.22 | 3.22 |
| 471.54 | 4.04 | 4.04 |