Basic Information
ID: ALA4190494
Type: Binding
Description: Proteolysis targeting chimera activity in human 22Rv1 cells assessed as induction of VHL-mediated delivery of c-MYC for protein degradation by proteasome by measuring drug level causing 50% substrate depletion incubated for 16 hrs by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4190494
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 986.66 | 6.53 | 6.53 |