Assay Report Card

Basic Information

ID: ALA4190499

Type: Binding

Description: Proteolysis targeting chimera activity in human K562 cells assessed as induction of cereblon-mediated delivery of BCR-ABL for protein degradation by proteasome at 1 uM after 24 hrs by immuno blot analysis relative to control

Organism: Homo sapiens

Cell type: K562

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1031.05
958.586.756.75