Basic Information
ID: ALA4190757
Type: Binding
Description: Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21(DE3)RP cells assessed as DNA ligation at 100 uM using fluorescently labelled ds nicked DNA as substrate after 30 mins by urea gel based imaging method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4190757
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 572.46 | 4.80 | 4.80 |
| 511.55 | 4.18 | 4.18 |
| 509.63 | 4.20 | 4.20 |
| 391.45 | 1.06 | 1.06 |
| 318.33 | 1.70 | 1.70 |
| 544.08 | 4.85 | 4.85 |
| 539.73 | 4.67 | 4.67 |
| 509.63 | 4.20 | 4.20 |
| 405.48 | 1.32 | 1.32 |
| 375.39 | 0.89 | 0.89 |
| 544.08 | 4.85 | 4.85 |
| 447.56 | 2.31 | 2.31 |
| 560.15 | 5.02 | 5.02 |
| 525.70 | 4.37 | 4.37 |
| 433.53 | 2.05 | 2.05 |
| 502.00 | 3.87 | 3.87 |
| 523.59 | 4.04 | 4.04 |
| 360.41 | 2.69 | 2.69 |
| 417.47 | 1.88 | 1.88 |