Basic Information
ID: ALA4190758
Type: Binding
Description: Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21(DE3)RP cells assessed as reduction in fluorescently labelled ds nicked DNA substrate ligation at 100 uM after 30 mins by urea gel based imaging method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4190758
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 572.46 | 4.80 | 4.80 |
| 511.55 | 4.18 | 4.18 |
| 509.63 | 4.20 | 4.20 |
| 391.45 | 1.06 | 1.06 |
| 318.33 | 1.70 | 1.70 |
| 544.08 | 4.85 | 4.85 |
| 539.73 | 4.67 | 4.67 |
| 509.63 | 4.20 | 4.20 |
| 405.48 | 1.32 | 1.32 |
| 375.39 | 0.89 | 0.89 |
| 544.08 | 4.85 | 4.85 |
| 447.56 | 2.31 | 2.31 |
| 560.15 | 5.02 | 5.02 |
| 525.70 | 4.37 | 4.37 |
| 433.53 | 2.05 | 2.05 |
| 502.00 | 3.87 | 3.87 |
| 523.59 | 4.04 | 4.04 |
| 360.41 | 2.69 | 2.69 |
| 417.47 | 1.88 | 1.88 |