Inhibition of recombinant human MMP3 (Tyr18 to Cys477 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate...

Basic Information

ID: ALA4193095

Type: Binding

Description: Inhibition of recombinant human MMP3 (Tyr18 to Cys477 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Target: Matrix metalloproteinase 3(ALA283)

Document: ALA4190296

Inhibition of recombinant human MMP3 (Tyr18 to Cys477 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4193095

IC50

Total(32)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
393.47	1.81	1.81
300.44	4.90	4.90
620.79	6.57	6.57
982.88	10.24	10.24
853.14	9.33	9.33
681.69	7.20	7.20
861.07	8.99	8.99
861.07	8.99	8.99
885.14	8.73	8.73
602.80	6.43	6.43
825.09	8.71	8.71
632.82	6.44	6.44
861.07	8.99	8.99
853.14	9.33	9.33
632.82	6.44	6.44
885.14	8.73	8.73
620.79	6.57	6.57
885.14	8.73	8.73
632.82	6.44	6.44
885.14	8.73	8.73
982.88	10.24	10.24
861.07	8.99	8.99
853.14	9.33	9.33
885.14	8.73	8.73
681.69	7.20	7.20
929.96	10.30	10.30
620.79	6.57	6.57
853.14	9.33	9.33
853.14	9.33	9.33
853.14	9.33	9.33
825.09	8.71	8.71
885.14	8.73	8.73