Basic Information
ID: ALA4193350
Type: Binding
Description: Activation of glucokinase in rat INS1(832/13) cells assessed as increase in glucose sensitive insulin secretion at 20 uM after 2 hrs in presence of 5.5 mM glucose by AlphaLISA method relative to control
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4193350
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.44 | 3.38 | 3.38 |
| 658.80 | 5.29 | 5.29 |
| 575.63 | 6.17 | 6.17 |
| 622.74 | 5.74 | 5.74 |
| 627.78 | 6.45 | 6.45 |
| 580.71 | 4.45 | 4.45 |
| 617.75 | 5.30 | 5.30 |
| 615.71 | 4.70 | 4.70 |
| 618.73 | 4.69 | 4.69 |
| 502.61 | 4.49 | 4.49 |
| 516.64 | 4.88 | 4.88 |
| 622.74 | 5.74 | 5.74 |
| 617.75 | 5.30 | 5.30 |
| 587.72 | 5.67 | 5.67 |
| 631.77 | 5.69 | 5.69 |
| 610.73 | 5.60 | 5.60 |
| 594.69 | 4.96 | 4.96 |
| 566.68 | 3.80 | 3.80 |
| 593.73 | 5.57 | 5.57 |
| 640.73 | 5.88 | 5.88 |
| 559.71 | 4.77 | 4.77 |
| 600.70 | 4.80 | 4.80 |
| 617.75 | 5.30 | 5.30 |
| 600.70 | 4.80 | 4.80 |
| 627.78 | 6.60 | 6.60 |
| 559.67 | 3.91 | 3.91 |
| 603.72 | 4.91 | 4.91 |
| 643.78 | 5.83 | 5.83 |
| 522.63 | 4.09 | 4.09 |
| 594.72 | 4.96 | 4.96 |
| 593.71 | 4.49 | 4.49 |
| 594.72 | 4.96 | 4.96 |
| 531.66 | 3.99 | 3.99 |
| 608.72 | 5.09 | 5.09 |
| 545.68 | 4.38 | 4.38 |
| 599.71 | 5.41 | 5.41 |
| 622.74 | 5.74 | 5.74 |
| 622.74 | 5.74 | 5.74 |
| 635.76 | 6.46 | 6.46 |
| 613.76 | 6.21 | 6.21 |
| 623.73 | 5.14 | 5.14 |
| 607.75 | 5.56 | 5.56 |
| 580.66 | 4.57 | 4.57 |
| 594.72 | 4.96 | 4.96 |
| 518.61 | 4.08 | 4.08 |
| 622.74 | 6.14 | 6.14 |
| 530.62 | 4.52 | 4.52 |