Basic Information
ID: ALA4193837
Type: Binding
Description: Inhibition of 5-LOX in RBL1 cells assessed as reduction in LTB4 production using A23187-induced arachidonic acid as substrate preincubated for 2 hrs followed by A23187 addition measured after 15 mins by LC-MS/MS analysis
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4193837
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 206.28 | 3.07 | 3.07 |
| 266.41 | 2.48 | 2.48 |
| 230.31 | 3.38 | 3.38 |
| 250.41 | 3.47 | 3.47 |
| 282.41 | 2.15 | 2.15 |
| 230.32 | 2.55 | 2.55 |
| 234.34 | 2.75 | 2.75 |