Basic Information
ID: ALA4194326
Type: Binding
Description: Inhibition of Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in purmorphamine-induced increase in alkaline phosphatase level using CDP-star as substrate pretreated for 1 hr followed by purmorphamine addition measured after 5 days by luminescence assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4194326
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.31 | 4.71 | 4.71 |
| 298.41 | 4.43 | 4.43 |
| 270.36 | 3.73 | 3.73 |
| 284.38 | 4.04 | 4.04 |
| 284.38 | 4.04 | 4.04 |
| 298.41 | 4.35 | 4.35 |
| 298.41 | 4.35 | 4.35 |
| 316.45 | 4.46 | 4.46 |
| 284.38 | 4.10 | 4.10 |
| 312.44 | 4.86 | 4.86 |
| 315.35 | 3.64 | 3.64 |
| 334.90 | 5.49 | 5.49 |
| 389.76 | 6.41 | 6.41 |
| 300.38 | 3.74 | 3.74 |
| 312.44 | 4.66 | 4.66 |
| 298.41 | 4.43 | 4.43 |
| 329.38 | 3.95 | 3.95 |
| 300.45 | 4.76 | 4.76 |
| 288.35 | 3.87 | 3.87 |
| 318.83 | 4.70 | 4.70 |
| 312.44 | 4.86 | 4.86 |
| 312.44 | 4.71 | 4.71 |
| 346.45 | 5.40 | 5.40 |
| 320.42 | 4.89 | 4.89 |
| 328.39 | 3.52 | 3.52 |
| 286.36 | 3.44 | 3.44 |
| 312.44 | 4.74 | 4.74 |