ID: ALA4195044
Type: Functional
Description: Negative allosteric modulation of rat mGlu2 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux at 10 uM preincubated for 5 mins followed by glutamate addition measured after 2 mins by BTC-AM-dye based fluorescence assay
Organism: Rattus norvegicus
Bioactivity
Activity Types for Assay ALA4195044
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
397.41 | 4.18 | 4.18 |