Assay Report Card

Basic Information

ID: ALA4195046

Type: Functional

Description: Negative allosteric modulation of rat mGlu4 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux at 10 uM preincubated for 5 mins followed by glutamate addition measured after 2 mins by BTC-AM-dye based fluorescence assay

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
397.414.184.18