Assay Report Card

Basic Information

ID: ALA4195050

Type: Functional

Description: Negative allosteric modulation of rat mGlu1 receptor expressed in HEK293 cells assessed as reduction in glutamate-induced calcium mobilization at 10 uM preincubated for 2.3 mins followed by glutamate addition measured after 2.6 mins by Fluo-4--AM dye based fluorescence assay

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
397.414.184.18