ID: ALA4195050
Type: Functional
Description: Negative allosteric modulation of rat mGlu1 receptor expressed in HEK293 cells assessed as reduction in glutamate-induced calcium mobilization at 10 uM preincubated for 2.3 mins followed by glutamate addition measured after 2.6 mins by Fluo-4--AM dye based fluorescence assay
Organism: Rattus norvegicus
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA4195050
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
397.41 | 4.18 | 4.18 |