Basic Information
ID: ALA4195475
Type: Binding
Description: Inhibition of human TLR7 expressed in HEK293 cells assessed as decrease in R848-induced NF-kappaB activation-mediated SEAP production at 5 uM after 24 hrs by Quanti-blue-based assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4195475
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.81 | 2.93 | 2.93 |
| 354.39 | 2.29 | 2.29 |
| 392.36 | 3.30 | 3.30 |
| 358.81 | 2.93 | 2.93 |
| 393.25 | 3.59 | 3.59 |
| 392.36 | 3.30 | 3.30 |
| 403.26 | 3.04 | 3.04 |
| 384.42 | 2.30 | 2.30 |
| 352.42 | 2.84 | 2.84 |
| 393.25 | 3.59 | 3.59 |
| 367.43 | 2.35 | 2.35 |
| 338.39 | 2.59 | 2.59 |
| 342.36 | 2.42 | 2.42 |
| 342.36 | 2.42 | 2.42 |
| 393.25 | 3.59 | 3.59 |