Basic Information
ID: ALA4195522
Type: Binding
Description: Inhibition of GlyT1 in primary rat cortical neurons assessed as reduction in [14C]glycine uptake after 2 hrs by microbeta scintillation counting method
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4195522
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.53 | 3.94 | 3.94 |
| 372.43 | 3.69 | 3.69 |
| 504.53 | 3.81 | 3.81 |
| 445.38 | 3.76 | 3.76 |
| 479.51 | 4.38 | 4.38 |
| 493.51 | 4.07 | 4.07 |
| 508.52 | 3.85 | 3.85 |
| 498.46 | 3.30 | 3.30 |
| 427.41 | 4.24 | 4.24 |
| 387.44 | 3.39 | 3.39 |
| 511.50 | 4.29 | 4.29 |
| 418.42 | 4.36 | 4.36 |
| 505.52 | 3.20 | 3.20 |
| 479.48 | 3.76 | 3.76 |
| 444.39 | 4.37 | 4.37 |
| 497.47 | 3.90 | 3.90 |
| 507.53 | 4.54 | 4.54 |
| 455.51 | 3.36 | 3.36 |
| 448.48 | 3.84 | 3.84 |
| 423.45 | 4.41 | 4.41 |
| 443.50 | 3.36 | 3.36 |
| 480.50 | 3.77 | 3.77 |
| 391.41 | 3.22 | 3.22 |
| 512.49 | 3.69 | 3.69 |
| 441.41 | 3.93 | 3.93 |
| 457.53 | 3.75 | 3.75 |
| 501.56 | 3.37 | 3.37 |
| 494.50 | 3.46 | 3.46 |
| 471.50 | 3.89 | 3.89 |
| 399.45 | 3.39 | 3.39 |