Basic Information
ID: ALA4195558
Type: Functional
Description: In vivo inhibition of GlyT1 in Sprague-Dawley rat assessed as increase in CSF glycine levels at 10 mg/kg, po administered as single dose measured after 90 mins by LC-MS/MS analysis relative to control
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4195558
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.38 | 3.76 | 3.76 |
| 387.44 | 3.39 | 3.39 |
| 497.47 | 3.90 | 3.90 |
| 455.51 | 3.36 | 3.36 |