Basic Information
ID: ALA4195563
Type: Binding
Description: Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4195563
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 509.74 | 5.84 | 5.84 |
| 492.66 | 5.44 | 5.44 |
| 478.64 | 5.18 | 5.18 |
| 381.48 | 4.33 | 4.33 |
| 478.64 | 5.04 | 5.04 |
| 473.62 | 5.05 | 5.05 |
| 520.72 | 6.21 | 6.21 |
| 450.58 | 4.45 | 4.45 |
| 532.73 | 6.22 | 6.22 |
| 546.76 | 6.74 | 6.74 |
| 516.69 | 5.57 | 5.57 |
| 425.53 | 4.08 | 4.08 |
| 518.70 | 5.83 | 5.83 |
| 504.68 | 5.71 | 5.71 |
| 518.70 | 5.96 | 5.96 |
| 479.62 | 5.15 | 5.15 |
| 504.68 | 5.43 | 5.43 |
| 496.63 | 5.13 | 5.13 |
| 466.63 | 4.90 | 4.90 |
| 492.66 | 5.43 | 5.43 |
| 464.61 | 4.70 | 4.70 |
| 490.65 | 5.04 | 5.04 |
| 520.72 | 6.21 | 6.21 |
| 518.70 | 5.96 | 5.96 |
| 502.66 | 5.04 | 5.04 |
| 506.69 | 5.83 | 5.83 |
| 464.61 | 4.88 | 4.88 |
| 502.66 | 5.32 | 5.32 |
| 448.61 | 5.17 | 5.17 |
| 421.54 | 5.25 | 5.25 |
| 532.73 | 5.93 | 5.93 |
| 504.68 | 5.57 | 5.57 |
| 466.58 | 4.22 | 4.22 |
| 508.66 | 4.67 | 4.67 |
| 506.69 | 5.68 | 5.68 |
| 518.70 | 5.82 | 5.82 |
| 532.61 | 6.07 | 6.07 |
| 476.62 | 4.79 | 4.79 |
| 483.06 | 5.83 | 5.83 |
| 504.68 | 5.57 | 5.57 |
| 504.68 | 5.57 | 5.57 |
| 544.74 | 6.35 | 6.35 |
| 518.70 | 5.68 | 5.68 |
| 449.60 | 6.03 | 6.03 |
| 492.66 | 5.21 | 5.21 |
| 492.62 | 4.71 | 4.71 |
| 471.60 | 6.29 | 6.29 |